Tossup

One of these molecules is chemically linked to a cytotoxic payload in an ADC, a form of targeted cancer therapy. HAT medium is used to incubate hybridomas in a technique for producing large (10[1])amounts of one type of these molecules. These molecules’ hinge regions connect their Fab (10[2])(“F-A-B”) and Fc (“F-C”) regions. The diversity of certain receptors and these molecules is facilitated through V(D)J recombination. (10[2])A type of these proteins that (10[1])only recognizes a single target is called “monoclonal.” These proteins can class-switch between their five isotypes and consist of two heavy chains and two light chains. For 10 points, B cells produce what Y-shaped proteins that bind to antigens? (10[1]0[1]-5[1])■END■ (10[1]0[1])

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