Tossup

One of these molecules is chemically linked to a cytotoxic payload in an ADC, a form of targeted cancer therapy. HAT medium is used to incubate hybridomas in a technique for producing large amounts of one type of these molecules. (10[1])These molecules’ hinge regions connect their Fab (10[1])(“F-A-B”) and Fc (10[1])(“F-C”) regions. The diversity of certain receptors and these molecules (-5[1])is facilitated through V(D)J recombination. (10[2])A type of these proteins that only recognizes a single target (-5[1])is called (-5[1])“monoclonal.” (10[1])These proteins can (10[1])class-switch between their five isotypes and consist of two heavy chains and two light chains. For 10 points, B cells produce (-5[1])what Y-shaped proteins that (10[1])bind to antigens? ■END■ (10[4])

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