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Round 6: Tossup 8

Note to moderator: read the answerline carefully. Note to players: specific term required. An effect is still elicited when this quantity is zero in the E-max model. Curves that show the “response” to this quantity can be fitted to the Hill equation and are sigmoidal in shape. This quantity is measured in grams per cubic meter or grams per kilogram of (-5[1])body weight depending on the route of application. (-5[1])The therapeutic index is equal to the ratio of two of these quantities. This quantity’s efficacy is related to concentration and duration of exposure. A form of this quantity required to kill half of all test subjects is (10[1])reported as the LD50, or this quantity’s “lethal” form. For 10 points, what quantity equals the amount of a drug (10[1])administered (-5[1])to (10[1])a patient? ■END■ (10[5]0[1])

ANSWER: doses [accept dosages; accept median lethal dose or semilethal dose or lethal dose, 50 percent or median effective dose; or median toxic dose; accept dose-response curves or dose-response relationships; prompt on stimulus response curve or stimulus response function by asking “what quantity acts as the stimulus?”; prompt on volume by asking “what is the more specific term?”; prompt on ED50 or TD50; prompt on descriptions of the amount of a drug or pharmaceutical until read by asking “what is the more specific term?”; prompt on LD50 or LC50 or LCt50 until “LD50” is read; prompt on concentration or lethal concentration or effective concentration until read by asking “what is the more specific term?”; prompt on exposure until read by asking “what is the more specific term?”]
<Editors, Chemistry> | Packet H
= Average correct buzz position

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Buzzes

PlayerTeamOpponentPositionValue
Anirudh TerdalLSEWarwick60-5
Michael ShipmanCambridge DImperial A68-5
Oliver WestCambridge BImperial C10610
James StadlerImperial BImperial D12610
Aeron WheelCardiffBristol127-5
Dan MillingtonBirminghamCambridge C12810
Ada BendelBristolCardiff13110
Mata CooperSouthamptonCambridge A13110
Nicholas HallCambridge EOxford1310
Nayaaz HashimOxfordCambridge E13110
David LatimerImperial ACambridge D13110
Jolie YehWarwickLSE13110

Summary

TournamentEditionTUHConv. %Neg %Average Buzz
UK (North)UK5100%0%108.20
UK (South)UK8100%38%126.88
Northern CaliforniaUS4100%75%123.25
Southern CaliforniaUS7100%57%116.43
Eastern Canada (1)US5100%20%101.80
Eastern Canada (2)US9100%22%114.11
FloridaUS4100%75%123.25
Great LakesUS11100%27%113.00
Lower Mid-AtlanticUS9100%0%113.11
Upper Mid-AtlanticUS12100%33%112.00
MidwestUS9100%44%117.22
NorthUS4100%25%114.50
NortheastUS12100%25%121.50
PacificUS8100%13%117.25
South CentralUS7100%29%122.71
SoutheastUS13100%23%116.92
Upstate NYUS5100%0%112.00